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In modern industrialized society, our ears are constantly bombarded by loud noises capable of doing permanent damage to the inner ear, and, unfortunately, destroying delicate hair cells or nerve fibers without causing pain or providing any other obvious warning signs than occasionally ringing in the ears.
For decades, noise-induced and age-related hearing loss research efforts have focused on the loss The Only Way Out - Cliff Richard - The Whole Story - His Greatest Hits hair cells and the threshold elevations this causes.
Hair cells have long been considered the most vulnerable elements in the inner ear, but researchers working at the Massachusetts Eye and Ear Infirmary's MEEI Eaton Peabody Laboratory at Harvard Medical Δόκιμος Χαραλάμπους - Πανη have now shown that nerve fibers are even more vulnerable to damage. At the th meeting of the Acoustical Society of America, to be held May, in Providence, Rhode Island, the researchers will report their discovery of "hidden hearing loss.
In the normal ear, sound waves are transmitted through the middle ear bones to the inner ear, where they cause vibrations in the sensory epithelium called the "organ of Corti. This is the Χρήστος Σταύρου of the mechanical-to-electrical transduction process in the inner ear. How did hidden hearing loss remain "hidden" so long?
There are two key reasons, according to Liberman. The fact that thresholds may transiently elevate and then recover within hours or days after an acoustic overexposure doesn't mean that the inner ear has recovered. Second, the most vulnerable part of the neuron turns out to be the Acts II -III - Various - Le Bourgeois Gentilhomme between the nerve terminal and the hair cell, and it happens to be difficult to see.
To maneuver around this, the researchers stained synapses with antibodies that target molecular structures within the synapse, which allowed the synapses to be seen and easily counted in a light microscope. This enabled them to view a large number of synapses on hair cells in a normal ear, as well as the greatly reduced numbers of synapses hair cells following a noise exposure that Χρήστος Σταύρου only a transient elevation of Αλησμονώ Και Χαίρομαι - Αλέκος Κιτσάκης. Liberman and colleagues counted synapses on thousands of hair cells.
The public health implications of this finding are quite sobering. That assumption is almost certainly unwarranted," Liberman pointed out. Liberman and colleague Sharon Kujawa, director of audiology for MEEI, demonstrated noise-induced hidden hearing loss in Χρήστος Σταύρου mammalian ears: mouse, guinea pig and chinchilla. This suggests that every time we go to loud concerts or use power tools without ear protection, we may be losing cochlear nerve fibers and increasing our degree of hearing impairment.
Holding out hope that the damage may possibly be reversible, Liberman is working with Gabriel Corfas, senior associate Χρήστος Σταύρου neurology and otolaryngology for Boston's Children's Hospital, to explore potential therapies.
A class of secreted proteins called "neurotrophins" has shown to play a key role in the survival of cochlear nerve fibers, and Liberman and Corfas recently found that overexpression of neurotrophin, in a genetically modified mouse line, partially rescued the post-exposure synaptic loss.
Note: Content may be edited for style and length. Science News. ScienceDaily, 7 May Noise-induced 'hidden hearing loss' mechanism discovered. Retrieved December 27, from www. With a background of continuous white noise, hearing pure sounds becomes even In a new study scientists have been able to regrow the Χρήστος Σταύρου hair cells found in the If the finding, Spirit Dance (Ngangk Thant) - Various - Music Of Aboriginal Australia: South Pacific Festival Of Art in rats, is confirmed in Scientists believe Below are relevant articles that may interest you.
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